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“After my wife’s oocytes had been fertilized by my sperm and some of the impregnated ova have developed into embryos, we now want to know which embryo is the one most suitable for being transferred to the uterus and what our chances are to achieve a pregnancy and the birth of a healthy child.“
What matters most to these intended parents – and what they share in common with many others – is that they want to know more about the development of their embryos. Embryo formation is probably one of the most important steps in the course of an IVF treatment. In order to evaluate the developmental potential of embryos prior to performing embryo transfer, the professional knowledge of experienced biologists is needed. Such assessment can be supported by using an assistive tool – the so-called “Time-Lapse Analysis”, which allows for monitoring embryonic development by means of time-lapse imaging using a special camera system (e.g. EmbryoScope). Subsequently, the embryo with the highest implantation potential (Single-Embryo-Transfer) is to be determined on the basis of pre-established criteria. This approach, of course, raises some questions:
Could it happen that embryos whose early development has to be regarded as suboptimal are nevertheless able to result in pregnancy and the birth of a healthy baby?
Moreover, can it be justified that instead of transferring these embryos, the focus is put on the success of a subsequent future IVF cycle – an attempt with an uncertain outcome?
To answer these questions, a study was carried out. The results have been published in the renowned scientific journal RBM Online. The study shows how important it is to do research in this field of reproductive medicine. Read more…