fertility treatment BLOG - IVF Zentren Prof. Zech
Flickr Pinterest YouTube E-mail
formats

“Good Swimmers” – but is this enough?

| Additional information as part of the semen analysis can be provided by molecular biological assessment of sperm quality

|

Icon image | Photo: Shutterstock

In the evaluation of male fertility through the analysis of a semen sample under a microscope, the desired outcome is to see a lot of “good swimmers” among the spermatozoa – although this still says little or nothing about their morphology and inner structure. Thanks to modern technologies, it is now possible to go into this in greater detail. This is done by extending semen analysis beyond the existing WHO criteria by adding so-called molecular diagnostics.

WHO criteria to serve as the basis

A spermiogram (semen analysis) implies an analysis of the ejaculate on the basis of standardized investigation methods and associated reference values laid down by the World Health Organization (WHO).
This spermiogram forms the foundation and provides a first overview of the situation as regards concentration, motility, vitality, structure and morphology of the spermatozoa. However, when dealing with involuntary childlessness, these parameters alone may not be sufficient for reliable detection of male factor infertility. Read more…

formats

Diagnosis: PCO Syndrome

| A syndrome with a complex nature as the potential cause of the involuntary childlessness

|

Icon image | Photo: Shutterstock

One evening, my friend Gudrun called, telling me that she had been diagnosed with PCO syndrome by her gynecologist. She asked me to exactly explain the disorder to her.

Gudrun is a healthy woman in her early 30s. She has taken the pill for several years for contraceptive purposes and to regulate her somewhat irregular menstrual cycle. Now that she has met Mr. Right and they wish to start a family, she has stopped taking the pill. But nothing happened so far – no menstrual bleeding and no pregnancy occurred. At first, Gudrun took a wait-and-see attitude. After 4 months, she went to see her gynecologist and was diagnosed with PCOS (polycystic ovary syndrome). “But I have a healthy lifestyle with a balanced diet and sufficient exercise,” says Gudrun. She had used the Internet to learn more about possible causes. Now she was at a loss what to do. She needed a personal clarification and remembered that I work for a fertility center.
Read more…

formats

Increased Risk of Hypertension due to IVF?

| A new study has created a great deal of uncertainty among patients

|

Icon image | Photo: Shutterstock

A recently published study (see link) conducted by a Swiss working group on the increased risk of high blood pressure in children conceived by assisted reproductive technologies (ART) is currently making big waves, not least through nonstop media coverage. Additionally, this was fueled by some statements made by the senior author of this publication. He insists that IVF should be considered as a cardiovascular risk factor, similar to the risk from smoking (NZZ of 7 September 2018).

Thus, the study suggests a direct correlation between IVF treatments and specific health risks. This, of course, leads to much uncertainty among couples who either have already started treatment or who are still considering the use of assisted reproductive technologies. Against this background, it is even more important for us at the IVF Zentren Prof. Zech to provide a scientifically well-founded analysis of this study in order to enable our patients to make informed, fact-based decisions. To this end, we have published a response letter (more to follow) in the specialist magazine Journal of the American College of Cardiology where the study was published. In that respect, we would like to give a few words of explanation. Read more…

formats

“What are our chances of achieving a pregnancy resulting in the birth of a healthy child?”

| FAQs on genetics within the context of fertility treatment

|
519_wp_1200px

Icon image | Photo: Shutterstock

IVF treatment with PGD/PGS might be an option for infertile couples who, despite all efforts, have still not become pregnant and whose diagnostic findings seem to be linked to the failure. However, the option is only available for couples who meet all the medical and legal requirements.

Basically, there are two terms for the aforementioned investigations, though referring to two distinct techniques (for more details see “links”). On the one hand, there is “Pre-Implantation Genetic Diagnosis” (PGD) – in German-speaking countries also referred to as “Pre-Implantation Diagnosis” (PID). On the other hand, there is “Pre-Implantation Genetic Screening” (PGS). These are analytic diagnostic procedures that may, for instance, be used in cases of individuals who are known carriers of a genetic disorder and/or have a history of a genetic disease in the family, recurrent miscarriage or multiple failed IVF attempts.

This underlines the importance of ensuring comprehensive consulting and clarification of the couple’s initial situation by an experienced medical specialist. Dr. Maximilian Murtinger, Medical Director of the IVF Centers Prof. Zech – Bregenz, is familiar with the questions that preoccupy the couples concerned: Read more…

formats

Hello “little polar bear”!

Cryo cycle after IVF

|

Icon image | Photo: Shutterstock

“It had finally worked out and I became pregnant with our little ‘polar bear’. Since yesterday, we are the proud parents of a healthy baby girl and we couldn’t be more thrilled.”

In this way or in a very similar one, couples talk about their experiences gained during IVF treatment involving a so-called ‘cryo cycle’. The procedure comprises the initial freezing of the embryo (fertilized oocyte in the early stages of its embryonic development) in order to thaw it at a later point in time and transfer it to the uterus (embryo transfer).

But why does the attending doctor opt for this kind of therapy? Read more…

formats

Dealing with the Loss

| Part 1 of the topic-series »Trying to conceive after a miscarriage«

|
[← article overview of the topic-series »Trying to conceive after a miscarriage«]
ivf_kinderwunsch_schwangerschaft_abort

Icon image | Photo: Shutterstock

As already announced, our topic-series shall, inter alia, give you an idea of how important it may be to seek psychological assistance after a miscarriage – in particular when the couple still shares the desire of having children. The initial focus will be on dealing with the experience of loss.

A miscarriage is not just that an existing pregnancy does not develop any further, but the intense longing and desire for a child are shattered, at least temporarily. This is why every miscarriage is a traumatic event. Read more…

formats

Close to nature

| IVF treatment involving blastocyst culture

|
#501_1200

Icon image | Photo: Shutterstock

The aim of this medical specialty can already be inferred from the term Reproductive Medicine. It means understanding and copying nature right down to the smallest details, i.e. supporting human procreation using medical-technical procedures designed to help sub-fertile couples. Based on current scientific knowledge, an important role is played by a treatment option called blastocyst culture.

During a thorough medical consultation at the beginning of each fertility treatment, the doctor, together with the couple, will decide on the most suitable form of treatment, based on laboratory results, diagnostic findings etc. Details on the medical indication, legal framework conditions as well as on the sequence of the treatment will also be taken into account during this consultation. Read more…

formats

Trying to conceive after a miscarriage

|
327_wp_1200px

Icon image | Photo: Shutterstock

A miscarriage is undoubtedly one of the worst things that can happen to a couple on their path towards their long awaited child. For those couples, it is something of a personal disaster to give up on their dream for which they had accepted much hardship and in which they had placed great hopes. At first, it seems to be almost impossible for them to recover from the shock and finally overcome this personal tragedy, especially when they do not seek help from an uninvolved third party. It is, therefore, no surprise that this is still considered a taboo subject by many couples concerned.

Who can they turn to for help in this painful situation? Read more…

formats

“What are the situations where egg donation may help?”

| FAQs on egg donation

|
517_wp_1200px

Icon image | Photo: Shutterstock

There are a variety of reasons why couples may want to use donated eggs to fulfil their dream of having a child. There are situations where couples cannot achieve a successful pregnancy with the woman’s own oocytes (e.g. cancer treatment, genetic diseases, premature menopause) and may therefore decide to try for conception with donor eggs and IVF.

First, however, each couple’s initial situation has to be assessed in a professional and comprehensive way and any questions the couple may have must be answered. MUDr. Libor Hradecký Ph.D., the Medical Director of the IVF Centers Prof. Zech in the Czech Republic, for instance, would be pleased to welcome you in Pilsen and provide you with detailed consultation. For 15 years now, he and his Pilsen-based team have helped couples realize their dream of having a child through donor egg IVF.

As an experienced practitioner of reproductive medicine, he is well aware of the questions preying on the minds of the couples concerned: Read more…

formats

Sperm quality

Assessment and significance in fertility treatments

|
329_wp_1200

Structure spermatozoon/oocyte | Photo: Shutterstock

Egg and sperm cell are of equal importance for the development of the embryo. A closer look at the sperm factor suggests that the assessment of sperm quality followed by the selection of appropriate spermatozoa for the fertilization of the oocyte are important steps on the path towards the much longed-for child.

During fertilization, signaling cascades are triggered inside the oocyte by the fertilizing sperm. During the fusion of the sperm and oocyte plasma, the release of a factor carried within the sperm head changes the calcium concentration in the oocyte cytoplasm. This again induces a series of subsequent reactions, finally enabling the fertilization of the oocyte.

It will therefore become all the more important to perform a comprehensive analysis of sperm morphology (shape, structure). An existing impairment (e.g. identification of vacuoles = crater-like structures in the sperm head) may have negative impacts. Already at the end of the 1990s, electron microscopic investigations revealed a correlation between the presence of vacuoles and the impairment of natural male fertility (Berkovitz et al., 1999). Read more…