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When the immune system is „up to no good“

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…then these patients suffer from so-called autoimmune diseases, such as Hashimoto’s thyroiditis. The disorder leads to a chronic inflammation of the thyroid, thus impairing the reproductive health of these patients. Patients undergoing treatment at the
IVF Centers Prof. Zech are routinely tested for Hashimoto’s thyroiditis and, if necessary, receive appropriate treatment.

The disorder was named after the Japanese physician Hakaru Hashimoto, who was the first to describe it in 1912. Hashimoto’s thyroiditis is a condition resulting from chronic inflammation of the thyroid gland (chronic lymphocytic thyroiditis). The “misguided” immune system mistakenly produces antibodies that attack healthy thyroid tissue and cause damage to it. The thyroid gland is part of the endocrine system and produces hormones that play an essential role in human metabolism.
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When pregnancy either fails to occur or ends tragically…

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…the underlying causes will be investigated. Couples who failed to conceive after several IVF attempts or who experienced recurrent pregnancy loss or repeated miscarriages are under particular strain. Worldwide, IVF specialists work feverishly on analyzing the reasons for miscarriages and embryo implantation failure in order to be able to provide successful therapy.

Many conditions during pregnancy are interpreted as disorders in the vascular supply and are considered to be a mild form of a so-called thromboembolic condition, i.e. a condition in which a blood clot forms inside a vessel (about 30% of the cases are concerned).
It is therefore important to recognize what impacts congenital or acquired coagulation disorders may have on human procreation and treat them accordingly. Read more…

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Having a career and children – you can do both

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Today, women are more highly educated and skilled than in the past. The proportion of women who graduated from high-school has greatly increased and there are more women on the executive floors than 10 years ago. However, there is a downside to this professional commitment: These days, women are postponing motherhood and family planning to a later age – and may suffer the consequences, because it might already be too late by then…

Birth Rate: Declining
There are fewer births in Switzerland, Germany, Italy and many other European countries. The state makes its best efforts to reverse the trend – however, child allowance, expansion of daycare centers for children, paternity leave, child care subsidy, and any other supporting action by the public authorities seem to be totally ineffective.
The declining birth rates have become (once again) a source of media attention, producing sobering headlines with monotonous regularity: “Germany – bottom of the league when it comes to birth rates in Europa“, “Not keen on KIDS“, “Having children is as unattractive as it has ever been“. Various studies attempt to provide explanations for this “trend” and blame it on the lack of child-friendliness, the concerns of women to depend again on outdated role models and, last but not least, on the most challenging problem of all: finding a way to balance career and family. Read more…

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Increased number of congenital malformations due to IVF?

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Is there in fact a correlation between higher rates of congenital defects in newborns and medically assisted reproduction?

How meaningful are corresponding studies that are relying solely on data collected from birth records – without indicating the techniques applied in the relevant fertility treatment?
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Precaution instead of worrying about the future

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Oocyte preservation is an option in modern life- and family planning. Today, physicians are increasingly approached with the request for fertility preservation. More and more women are discovering the benefits of having their oocytes cryopreserved in order to postpone motherhood and have children later in life. Read more…

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Risks and side effects lurk in everyday life …

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Whether it is about foodstuffs, body care products, cleaning agents or other everyday items, we are constantly exposed to various additives, emulsifiers, flavor enhancers, preserving agents, colorants, chemicals and many other harmful substances. Depending on their relevant substance class and quantity, these compounds may present a health hazard, can be irritant, poisonous and/or have a negative impact on our reproductive health. Read more…

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Fear of injections?

by | Published on 20. July 2013, in Treatment.
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If so, you are only one among many! For many patients, the start of an IVF treatment is associated with a great deal of discomfort, since the regular injections of hormone preparations present a major challenge to them. This is perfectly normal and absolutely understandable.

Most patients, however, will get used to giving themselves injections after having overcome the demanding initial phase. After all, the injections bring you closer to fulfilling your dream of conceiving and giving birth to your longed-for child. Read more…

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Stress test for spermatozoa

Egg and sperm contribute equally to the successful development of the embryo. Nuclear vacuoles in the sperm head are associated with reduced natural fertility in men. Questions arise about what causes the nuclear vacuolization.

Do we, as biologists, even promote the development of vacuoles in the laboratory without knowing?

Analysis of nuclear vacuoles at 6.000-X magnification

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Visit to the Bosporus

by | Published on 6. July 2013, in Science.
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The center of Istanbul is part of the UNESCO World Cultural Heritage – Another heritage, namely the genetic heritage, was at the heart of the 12th International Medical Conference of the Preimplantation Genetics Diagnosis International Society (PGDIS) which has been held recently in the city on the Bosporus. Last year, Bregenz was the host of the Congress and Nicolas Zech (Medical Director of the IVF Centers Prof. Zech) presided over it as chairman.

Nicolas Zech participated as a speaker in the Istanbul Congress. His lecture around the topic of PGD, preimplantation genetic diagnosis (option in fertility treatment for the diagnosis of genetic defects in embryos), referred, among other things, to the following examination techniques: polar body analysis, blastomere biopsy, biopsy of blastocysts as well as to specific indications for the use of PGD:
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New POWER through a new STANDARD

“It is time to explore new avenues in fertility treatment and to establish a new standard: the EGP (Expected Gametes Performance)“, explains Nicolas Zech, Medical Director of the IVF Centers Prof. Zech in Bregenz. This is intended to allow the optimal creation of the couples’ individual profiles in order then to make accurate predictions regarding pregnancy rate and birthrate.

As founders of the EGP, the IVF Centers Prof. Zech have recently published an article on this issue in the Journal of Assisted Reproduction and Genetics, an internationally leading professional journal in the field of assisted reproductive medicine. At forthcoming conferences and future meetings, the optimum EGP parameters are to be discussed and, subsequently, to be defined together with interested experts and other IVF centers.

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