fertility treatment BLOG - IVF Zentren Prof. Zech
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Dealing with the Loss

Part 1 of the topic-series »Trying to conceive after a miscarriage«

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[← article overview of the topic-series »Trying to conceive after a miscarriage«]
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As already announced, our topic-series shall, inter alia, give you an idea of how important it may be to seek psychological assistance after a miscarriage – in particular when the couple still shares the desire of having children. The initial focus will be on dealing with the experience of loss. Read more…

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Close to nature

IVF treatment involving blastocyst culture

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The aim of this medical specialty can already be inferred from the term Reproductive Medicine. It means understanding and copying nature right down to the smallest details, i.e. supporting human procreation using medical-technical procedures designed to help sub-fertile couples. Based on current scientific knowledge, an important role is played by a treatment option called blastocyst culture.

During a thorough medical consultation at the beginning of each fertility treatment, the doctor, together with the couple, will decide on the most suitable form of treatment, based on laboratory results, diagnostic findings etc. Details on the medical indication, legal framework conditions as well as on the sequence of the treatment will also be taken into account during this consultation. Read more…

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Trying to conceive after a miscarriage

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A miscarriage is undoubtedly one of the worst things that can happen to a couple on their path towards their long awaited child. For those couples, it is something of a personal disaster to give up on their dream for which they had accepted much hardship and in which they had placed great hopes. At first, it seems to be almost impossible for them to recover from the shock and finally overcome this personal tragedy, especially when they do not seek help from an uninvolved third party. It is, therefore, no surprise that this is still considered a taboo subject by many couples concerned.

Who can they turn to for help in this painful situation? Read more…

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“What are the situations where egg donation may help?”

FAQs on egg donation

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The couples’ requirements may vary considerably when it comes to achieving a pregnancy via egg donation.
There are situations where couples cannot achieve a successful pregnancy with the woman’s own oocytes (e.g. cancer treatment, genetic diseases, premature menopause) and would therefore have to consider IVF treatment with egg donation.

First, however, each couple’s initial situation has to be assessed in a professional and comprehensive way and any questions the couple may have must be answered. For example by MUDr. Libor Hradecký Ph.D., the Medical Director of the IVF Centers Prof. Zech in the Czech Republic. For 15 years now, he and his Pilsen-based team have helped couples realize their dream of having a child through IVF treatment with donor eggs.

As an experienced practitioner of reproductive medicine, he knows about the issues couples considering this kind of treatment are most concerned about: Read more…

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Sperm Quality

Assessment and Significance in Fertility Treatments

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Egg and sperm cell are of equal importance for the development of the embryo. A closer look at the sperm factor suggests that the assessment of sperm quality followed by the selection of appropriate spermatozoa for the fertilization of the oocyte are important steps on the path towards the much longed-for child.

During fertilization, signaling cascades are triggered inside the oocyte by the fertilizing sperm. During the fusion of the sperm and oocyte plasma, the release of a factor carried within the sperm head changes the calcium concentration in the oocyte cytoplasm. This again induces a series of subsequent reactions, finally enabling the fertilization of the oocyte.

It will therefore become all the more important to perform a comprehensive analysis of sperm morphology (shape, structure). An existing impairment (e.g. identification of vacuoles = crater-like structures in the sperm head) may have negative impacts. Already at the end of the 1990s, electron microscopic investigations revealed a correlation between the presence of vacuoles and the impairment of natural male fertility (Berkovitz et al., 1999). Read more…

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An impuls towards parenthood

Hormonal stimulation in fertility treatment

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Precisely tailored to the woman’s individual situation, her body is prepared for pregnancy prior to receiving fertility treatment. The ovaries are stimulated with hormones, which is an important first step towards the long-awaited child.

The targeted administration of hormones is intended to induce the maturation of multiple follicles, each containing an oocyte. In medical terms, this kind of treatment is referred to as ovarian stimulation (→ details). Read more…

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Cumulative pregnancy rate

Part 5 of the topic-series »Success Rate«

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[← article overview of the topic-series “Success Rate”]


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When analyzing success rates in fertility treatment, it often turns out that the stated values refer to cumulative pregnancy rates. But what exactly is meant by this type of pregnancy rate?

Cumulative is derived from the Latin word “cumulare” (to accumulate).
According to experts, the cumulative pregnancy rate takes account of all pregnancies achieved by IVF following several successive embryo transfers. Irrespective of whether these embryos derive from so-called “fresh cycles” (the fertilized oocyte develops inside an incubator and is usually transferred to the uterus on the fifth day of embryonic development) or from “cryo cycles” (for some reasons, the growing embryo can be frozen/cryopreserved, the frozen-thawed embryo can then be used in a future transfer).

Read more…

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“Natural cycle IVF”

IVF treatment in an unstimulated cycle

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Graphic representation female cycle | Photo: Shutterstock

For many women, starting fertility treatment is often associated with discomfort, since it entails hormone therapy involving the injection of specific preparations. Most women get used to it quickly, since what it does mean in any case is that they advance further on their way leading to the much longed-for aim: a child of their own.

Some women, however, are looking for an IVF therapy necessitating either a few doses of hormones or none at all. Terms such as “Natural cycle IVF” or “Mild Stimulation IVF” are bound to arouse interest and may sound promising at first. Read more…

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“When can I take the pregnancy test and what happens next?”

FAQs on fertility treatment

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Before and during fertility treatment, patients are often faced with a lot of impressions and information. Sometimes, however, this can be highly confusing, giving rise to a large number of questions.

After asking around, I discussed the issues with Univ. Prof. Dr. Herbert Zech, a specialist in reproductive medicine and founder of the IVF centers of the same name. Below please find his answers to some frequently asked questions:
Read more…

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… and if it doesn’t work?

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Doctors, medical assistants and embryologists in the laboratory, IT department, hygiene specialists, Info Center etc. We, as a team at the IVF Centers Prof. Zech dedicate our entire know-how and passion to helping infertile couples achieve a pregnancy with the help of assisted reproductive technology (ART).

In many cases, the patients are able to deliver the good news to us that their pregnancy test had come back positive and, later on, fetal heartbeat could be detected via ultrasound.
We particularly enjoy receiving cards or letters from happy parents in which they express their gratitude after the birth of their baby.

However, there are couples who get no chance of experiencing this kind of happiness. Read more…